| Shardtooth E'ko | 1 | | | Quest |
| Shardtooth Meat | 1 | | | Quest |
| Sharp Canine | 1 | | | Junk |
| Sharpbeak's Feather | 1 | | | Quest |
| Shattered Necklace | 1 | | | Quest |
| Shattered Necklace Power Source | 1 | | | Quest |
| Shattered Necklace Ruby | 1 | | | Quest |
| Shattered Necklace Sapphire | 1 | | | Quest |
| Shattered Necklace Topaz | 1 | | | Quest |
| Shattered Sword of Marduk | 1 | | | Quest |
| Shaw's Report | 1 | | | Quest |
| Shay's Bell | 1 | | | Quest |
| Sheaf of Cards | 1 | | | Consumable |
| Sheathed Trol'kalar | 1 | | | Quest |
| Shed Lizard Skin | 1 | | | Junk |
| Shellfish | 1 | | | Junk |
| Shimmering Basilisk Skin | 1 | | | Junk |
| Shimmering Frond | 1 | | | Quest |
| Shimmerweed | 1 | | | Quest |
| Shindrell's Note | 1 | | | Quest |
| Shiny Bracelet | 1 | | | Junk |
| Shiny Dinglehopper | 1 | | | Junk |
| Shiny Fish Scales | 1 | | | Junk |
| Shiny Polished Stone | 1 | | | Junk |
| Shiny Seashell | 1 | | | Junk |
| Shipment of Boots | 1 | | | Quest |
| Shipment of Iron | 1 | | | Quest |
| Shipment to Galvan | 1 | | | Quest |
| Shipment to Nethergarde | 1 | | | Quest |
| Shredder Operating Manual - Chapter 1 | 1 | | | Quest |
| Shredder Operating Manual - Chapter 2 | 1 | | | Quest |
| Shredder Operating Manual - Chapter 3 | 1 | | | Quest |
| Shredder Operating Manual - Page 1 | 1 | | | Junk |
| Shredder Operating Manual - Page 10 | 1 | | | Junk |
| Shredder Operating Manual - Page 11 | 1 | | | Junk |
| Shredder Operating Manual - Page 12 | 1 | | | Junk |
| Shredder Operating Manual - Page 2 | 1 | | | Junk |
| Shredder Operating Manual - Page 3 | 1 | | | Junk |
| Shredder Operating Manual - Page 4 | 1 | | | Junk |
| Shredder Operating Manual - Page 5 | 1 | | | Junk |