| Empty Vial Labeled #1 | 1 | | | Consumable |
| Empty Vial Labeled #2 | 1 | | | Consumable |
| Empty Vial Labeled #3 | 1 | | | Consumable |
| Empty Vial Labeled #4 | 1 | | | Consumable |
| Empty Wallet | 1 | | | Junk |
| Empty Water Tube | 1 | | | Quest |
| Empty Water Vial | 1 | | | Quest |
| Empty Worg Pup Cage | 1 | | | Quest |
| Empty Wrapper | 1 | | | Junk |
| Empty Writhing Haunt Bottle | 1 | | | Quest |
| Encased Corrupt Ooze | 1 | | | Quest |
| Encased Fiery Essence | 1 | | | Quest |
| Enchanted Agate | 1 | | | Quest |
| Enchanted Coral | 1 | | | Quest |
| Enchanted Gaea Seeds | 1 | | | Quest |
| Enchanted Resonite Crystal | 1 | | | Quest |
| Enchanted Scarlet Thread | 1 | | | Quest |
| Enchanted Sea Kelp | 1 | | | Quest |
| Encoded Fragment | 1 | | | Quest |
| Encrusted Minerals | 1 | | | Quest |
| Encrusted Silithid Object | 1 | | | Quest |
| Encrusted Tail Fin | 1 | | | Quest |
| Encrypted Letter | 1 | | | Quest |
| Encrypted Memorandum | 1 | | | Quest |
| Encrypted Parchment | 1 | | | Quest |
| Encrypted Rune | 1 | | | Quest |
| Encrypted Scroll | 1 | | | Quest |
| Encrypted Sigil | 1 | | | Quest |
| Encrypted Tablet | 1 | | | Quest |
| Encrypted Twilight Text | 1 | | | Quest |
| Engineer's Shield 1 | 1 | 1 | Off Hand | Shield |
| Engineer's Shield 2 | 1 | 1 | Off Hand | Shield |
| Engineer's Shield 3 | 1 | 1 | Off Hand | Shield |
| Eric Test Item A | 1 | 1 | | Consumable |
| Eric Test Item B | 1 | 1 | | Consumable |
| Eridan's Supplies | 1 | | | Quest |
| Eridan's Vial | 1 | | | Quest |
| Essence of Hakkar | 1 | | | Consumable |
| Essence of Nightlash | 1 | | | Quest |
| Essence of the Elements | 1 | | | Quest |