| Essence of the Exile | 1 | | | Consumable |
| Essence of the Firelord | 1 | | | Quest |
| Essence of the Firelord DEPRECATED | 1 | 100 | | Quest |
| Essence of Xandivious | 1 | | | Quest |
| Essential Artificial | 1 | | | Quest |
| Etched Note | 1 | | | Quest |
| Etched Parchment | 1 | | | Quest |
| Etched Phial | 1 | | | Quest |
| Etched Rune | 1 | | | Quest |
| Etched Sigil | 1 | | | Quest |
| Etched Tablet | 1 | | | Quest |
| Eternal Eye | 1 | | | Consumable |
| Eternal Quintessence | 1 | | | Quest |
| Evergreen Herb Casing | 1 | | | Quest |
| Evergreen Pouch | 1 | | | Quest |
| Everlook Report | 1 | | | Quest |
| Evermurky | 1 | | | Consumable |
| Evil Bat Eye | 1 | | | Junk |
| Evoroot | 1 | | | Quest |
| Example Collar | 1 | | | Quest |
| Executioner's Key | 1 | | | Consumable |
| Exorcism Censer | 1 | | | Quest |
| Explosive Stick of Gann | 1 | | | Quest |
| Extended Annals of Darrowshire | 1 | | | Quest |
| Extinguished Torch | 1 | | | Junk |
| Extra-Dimensional Ghost Revealer | 1 | | | Quest |
| Extraordinary Egg | 1 | | | Quest |
| Eye of Kajal | 1 | | | Quest |
| Eye of the Emberseer | 1 | | | Quest |
| Faded Photograph | 1 | | | Quest |
| Faded Shadowhide Pendant | 1 | | | Quest |
| Faerie Dragon Muisek | 1 | | | Quest |
| Faerie Dragon Muisek Vessel | 1 | | | Quest |
| Faint Necrotic Crystal | 1 | 1 | | Quest |
| Falconcrest's Head | 1 | | | Quest |
| Fallen Moonstone | 1 | | | Quest |
| False Documents | 1 | | | Junk |
| Familiar Claw | 1 | | | Junk |
| Familiar Fang | 1 | | | Junk |
| Familiar Hide | 1 | | | Junk |