| Rune-Inscribed Note | 1 | | | Quest |
| Rune-Inscribed Parchment | 1 | | | Quest |
| Rune-inscribed Pendant | 1 | | | Quest |
| Rune-Inscribed Tablet | 1 | | | Quest |
| Runes of Summoning | 1 | | | Quest |
| Rusted Engineering Parts | 1 | | | Junk |
| Rusted Iron Key | 1 | | | Key |
| Ryedol's Lucky Pick | 1 | | One-Hand | Miscellaneous |
| Ryson's Beacon | 1 | | | Quest |
| Ryson's Beacon | 1 | | | Quest |
| Sabertooth Fang | 1 | | | Junk |
| Sack of Barley | 1 | | | Quest |
| Sack of Corn | 1 | | | Quest |
| Sack of Gems | 1 | | | Junk |
| Sack of Homemade Bread | 1 | | | Consumable |
| Sack of Murloc Heads | 1 | | | Quest |
| Sack of Rye | 1 | | | Quest |
| Sack of Spoils | 1 | | | Junk |
| Sack of Supplies | 1 | | | Quest |
| Sacred Cord | 1 | | | Quest |
| Sacred Frostsaber Meat | 1 | | | Quest |
| Sacred Highborne Writings | 1 | | | Quest |
| Sacred Mallet | 1 | | | Quest |
| Salty Scorpid Venom | 1 | | | Quest |
| Sam's Tome | 1 | | | Book |
| Samha Essence | 1 | | | Quest |
| Samophlange | 1 | | | Quest |
| Samophlange Manual | 1 | | | Quest |
| Samophlange Manual Cover | 1 | | | Quest |
| Samophlange Manual Page | 1 | | | Consumable |
| Sample Elven Gem | 1 | | | Quest |
| Sample Ichor | 1 | | | Quest |
| Sample of Indurium Ore | 1 | | | Quest |
| Sample of Zanzil's Altered Mixture | 1 | 1 | | Junk |
| Sample Snapjaw Shell | 1 | | | Quest |
| Samuel's Remains | 1 | | | Quest |
| Sandfury Coin | 1 | | | Quest |
| Sandy Scorpid Claw | 1 | 1 | | Trade Goods |
| Sapphire of Aku'Mai | 1 | | | Quest |
| Sapphire of Sky | 1 | | | Quest |