| Scarlet Archive | Goober |
| Scarlet Cannon | Goober |
| Scarlet Cannon | Goober |
| Scarlet Crusade Forward Camp | Spell Focus |
| Scarlet Footlocker | Chest |
| Scarlet Watch Post | Generic |
| Scattered Crate | Chest |
| Schematic: Field Repair Bot 74A | Quest Giver |
| Scholomance Door | Door |
| Scholomance Trap - Door 01 | Trap |
| Scholomance Trap - Door 02 | Trap |
| Scholomance Viewing Room Spell Focus (DND) | Spell Focus |
| School of Deviate Fish | Fishing Hole |
| School of Fish | Fishing Hole |
| School of Tastyfish | Fishing Hole |
| Scorching Fire | Spell Focus |
| Scott's Cannon | Goober |
| Scourge Banner | Generic |
| Scourge Campfire | Spell Focus |
| Scourge Cauldron | Quest Giver |
| Scourge Cauldron | Quest Giver |
| Scourge Cauldron | Quest Giver |
| Scourge Cauldron | Quest Giver |
| Scourge Data | Chest |
| Scourge Generator | Trap |
| Scourge Structure | Goober |
| Scrimshank's Surveying Gear | Chest |
| Scrying Bowl | Quest Giver |
| Seal Destroyed Flame | Generic |
| Seal of Khaz'Mul | Door |
| Seal of the Earth | Quest Giver |
| Sealed Barrel | Quest Giver |
| Sealed Crate | Quest Giver |
| Sealed Supply Crate | Quest Giver |
| Searing Gorge | Generic |
| Searing Gorge | Generic |
| Seaworn Altar | Spell Focus |
| Second Witherbark Cage | Goober |
| Secret Door | Door |
| Secret Door | Door |