| Trelane's Orb | 1 | | | Quest |
| Trelane's Phylactery | 1 | | | Quest |
| Trelane's Wand of Invocation | 1 | | | Quest |
| Treshala's Pendant | 1 | | | Quest |
| Triage Bandage | 1 | | | Quest |
| Tribal Raptor Feathers | 1 | | | Junk |
| Trogg Stone Tooth | 1 | | | Quest |
| Troll Charm | 1 | | | Quest |
| Troll Sweat | 1 | | | Junk |
| Troll Temper | 1 | | | Quest |
| Trophy Raptor Skull | 1 | | | Junk |
| Trophy Swoop Quill | 1 | | | Quest |
| Troyas' Stave | 1 | | | Quest |
| Truesilver Shafted Arrow | 1 | | | Junk |
| Tuft of Gorilla Hair | 1 | | | Junk |
| Tumbled Crystal | 1 | | | Quest |
| Tunnel Rat Ear | 1 | | | Quest |
| Turtle Box | 1 | | | Junk |
| Tuxedo Shirt | 1 | | Shirt | Miscellaneous |
| TWAIN TEST ITEM VISUAL SWORD | 1 | 1 | One-Hand | Sword |
| Twilight Cultist Medallion of Station | 1 | | Neck | Junk |
| Twilight Pendant | 1 | | | Quest |
| Twilight Tablet Fragment | 1 | 1 | | Quest |
| Twilight Whisker | 1 | | | Quest |
| Twitching Antenna | 1 | | | Quest |
| Two of Beasts | 1 | | | Junk |
| Two of Elementals | 1 | | | Junk |
| Two of Portals | 1 | | | Junk |
| Two of Warlords | 1 | | | Junk |
| Tyranis' Pendant | 1 | | | Quest |
| Tyranis' Pendant (old) | 1 | | | Quest |
| U'cha's Pelt | 1 | | | Quest |
| Ukor's Burden | 1 | | | Consumable |
| Umbral Ore | 1 | | | Quest |
| Umi's Mechanical Yeti | 1 | | | Quest |
| Un'Goro Ash | 1 | | | Quest |
| Un'Goro Gorilla Pelt | 1 | | | Quest |
| Un'Goro Slime Sample | 1 | | | Quest |
| Un'Goro Soil | 1 | | | Junk |
| Un'Goro Stomper Pelt | 1 | | | Quest |